Concept Life Sciences brings together experts in mechanistic toxicology, preclinical services, and analytical services, as well as medicinal chemistry, specialist chemistry, translational biology, ADMET & DMPK.Our investigative toxicology group are acknowledged experts in the design, performance and interpretation of pre-clinical investigative and mechanistic toxicology programmes. Our experience spans the pharmaceutical, agrochemical, chemical and consumer products industries and the mechanistic data we generate is frequently used in submissions to regulators. We are also experts in discovery and exploratory toxicology, designing and performing experiments to characterise potential (for example on-target) or observed toxicity issues. Through an understanding of mechanistic toxicology at this early research stage, we can generate information that informs molecule design, candidate selection and translational risk assessment.Concept Life Sciences also has one of the widest ranges of analytical techniques and services available in Europe. Equipment is operated to GLP, cGMP and ISO 17025 quality standards to deliver high quality method development, validation and sample analysis.A combination of solid state and chromatographic instrumentation provides a one-stop platform for specialist services including materials characterisation, reference standard synthesis, bioanalysis, impurity / metabolite identification and synthesis, stability studies and trace analysis
At Concept Life Sciences, Dundee, we use our extensive industry experience and understanding of biological mechanisms to deliver tailored preclinical services:
- Investigative and Mechanistic Toxicology: By understanding the pathways that define the sensitivity of cells to chemicals, we evaluate the actual hazard to man, and rescue chemicals and drugs that may otherwise be abandoned.
- Exploratory & Discovery Toxicology: In order to improve productivity, Concept Life Sciences, Dundee can help you shift the identification of potential toxic hazard and risk from the development stage to the research stage of R&D.
- Agrochemical Metabolism and PK Support: Concept Life Sciences, Dundee routinely works with agrochemical companies to generate metabolic profiling data for new products, data gap fill and update to new regulations to support resubmissions.
- Drug Development Solutions: Accelerating lead selection and optimisation via in vitro and in vivo preclinical studies.